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This aligns with how growth hormone is metabolized and used by the body over time, since tissue repair benefits typically build gradually across several weeks rather than appearing immediately

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siRNA targeting LRP5 (GGACAGACUCAGAGAGACCAA) was transferred into the BMSCs with the help of Lipofectamine 3000 (Invitrogen, United States), and all operations were carried out under the manufacturers instructions

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Gut 63 , 727735 (2014)