In a 2021 trial of semaglutides, lean mass was reduced by 6.92kg alongside an overall weight drop of 15.3kg, meaning around 45% of the weight lost came from lean mass, comfortably exceeding the commonly cited quarter fat-free mass rule that predicts about one quarter of weight loss typically comes from lean tissue
Aim for 0.7-1g per pound of body weight daily
If you need a refresher on proper technique, the common peptide mistakes guide covers this and other errors in detail
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After sharing my weight loss journey using GLP-1 medications like semaglutide a few years ago, I wanted to follow up with my experience focusing on body compositionspecifically, how I was able to lose fat while gaining muscle