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Adverse Reactions / Side Effects Nausea Diarrhea Decreased appetite Vomiting Constipation Dyspepsia (indigestion) Abdominal pain If side effects are severe or persistent, contact your healthcare provider

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Importantly, tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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