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Both in vitro and in vivo experiments demonstrated that the delivery of miR-133b via MSC-EVs promotes neuronal growth (108)

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In addition, it is necessary to clarify the pharmacodynamic material basis of compound preparations through spectrum-effect relationship analysis, systematically conduct pharmacokinetic studies to optimize absorption and distribution characteristics, and utilize nanotechnology, such as metal-organic framework carriers and exosome biomimetic delivery, to develop intelligent delivery systems targeting pulmonary blood vessels and immune cells