The risk is lower when combined with metformin alone
Every athlete was like super-flat, super-thin and beautiful, but in a different way." Read on for more stars who have discussed using GLP-1 medications, like Ozempic
Some users describe feeling slightly nauseous, particularly during initial doses
Antioxidants & Redox Signaling, 2002
GLP-1 Agonists Market: COMPANY EVALUATION MATRIX In the GLP-1 agonists market matrix, Novo Nordisk (Star) stands out as the leading player, supported by a strong product portfolio and global market presence, driving widespread usage in diabetes and obesity management
For example, a Cleveland Clinic study from June 2025, involving 7,881 participants, found that high-dose tirzepatide users lost 18.0% of their body weight in one year, semaglutide users lost 13.7%, and those who discontinued early (within three months) lost just 3.6%