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Muscle aches appeared in 58% of patients, while true arthralgia (joint pain) was uncommon

Application: apply to clean dry skin, avoiding the area around the eyes and lips, after 15 - 20 minutes, carefully remove from the bottom-up, wash off the mask

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These symptoms typically emerge or worsen during treatment initiation and dose escalation, and often improve as the body adjusts to the medication over several weeks

Visalli, V., Muscoli, C., Sacco, I., et al