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Kynurenine (KYN) is transported across the BBB and metabolized by glial cells into KYNA and quinolinic acid (221, 222) ultimately resulting in excessive KYNA production
Endothelial and progenitor-cell migration model
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S.MaulikN.DasD
Seutter E et al
Our goal has been to do enough proof-of-principle that people will accept that stapled peptides can get into cells and act on important targets
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