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Consent to Participate Informed consent was obtained from all individual participants included in the study
Injectable GLP-1s studied for weight loss (like Wegovy and Zepbound) have produced substantial average weight loss in trials when combined with diet and exercise
Approximately 10% of POMC + neurons in the arcuate nucleus co-express GLP-1R and leptin receptors, and chemogenetic activation of POMC Glp1r+ neurons leads to reduced food intake in male mice (Biglari et al., 2021)
(PubMed) Bone RC, Balk RA, Cerra FB, et al
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