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It was reported by researchers that TB-500 might be action specific on the Notch3-Col 3A-CTGF gene axis in MCT-influenced mice, which appeared to result in the case of the test study in decreasing the right ventricular heart cell hypertrophy by a significant amount

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

All animals were treated humanely, and all studies were carried out in accordance with good laboratory practice (GLP) (China Food and Drug Administration, CFDA) guidelines for nonclinical laboratory studies of drugs issued by the National Scientific and Technological Committee of the Peoples Republic of China

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Videre forskning p 1980- og 1990-tallet avdekket at GHK-Cu ikke bare stimulerte kollagenproduksjon, men ogs akselererte srheling, reduserte arrdannelse og hadde anti-inflammatoriske egenskaper