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We do have to be careful about excess body weight loss, which we know sarcopenia, bone health, and so forth but we really haven't seen any other signals to date, and we're going to continue and look for those
The key difference appears to be dosage
Incretins, however, are rapidly degraded by dipeptidyl peptidase-4 resulting in fleeting half-lives of 12 min (Fig
Many literatures proved that GLP-1 derivatives performed neuroprotective effects and inhibited neuronal apoptosis ( Figure 1 There are also a type of non-peptide small molecules, which are mainly extracted from herbal medicine, such as Cornus officinalis , Gardenia jasminoides , Rehmannia glutinosa , Lamiophlomis rotata , and Strychnos nuzi ( Even for patients without complications of diabetes, their cognitive functions were still significantly improved ( 3 The neuroprotection of GLP-1RA in experimental stroke Many literatures indicated that GLP-1RA were also considered as the latent intervention strategy against ischemic stroke to improve the pathological symptoms and prognosis
90 , e72e74 (2010)