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1 2 Proceedings of the National Academy of Sciences of the United States of America
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Intrinsic factor deficiency causes pernicious anemia, which may be associated with subacute combined degeneration of the spinal cord
Eligible studies included randomised controlled trials, cohort, and case-control studies assessing B12 supplementation efficacy via oral, sublingual, or IM administration routes
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This decline is a key contributor to the common signs of aging (think wrinkles, decreased mobility, reduced mental clarity, and low energy)
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