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And importantly, NAD + levels decline with age and metabolic disease

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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency

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However, you may see results sooner when you maintain proper diet and exercise

A persons doctor can provide them with information about any specific activities they may need to avoid or any other considerations