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New agents were developed since with the aim of reducing elevated glucose levels while limiting the risk of hypoglycemia

Clinical trials showed that recipients using weekly doses experienced a mean weight loss of up to 20% at 72 weeks

Management strategies include ensuring adequate protein intake (1.2-1.6 g/kg ideal body weight daily), maintaining proper hydration, considering dose adjustment or delayed escalation, engaging in regular physical activity, and working with a registered dietitian

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