Body weight and BMI Higher weight or BMI may require a higher dosage to achieve the same appetite-suppressing and metabolic effects
Reducing that fat burden does not cure the autoimmune condition, but it may lower the baseline inflammatory level enough that existing treatments work more effectively
Jiao Y, Wang Y, Guo S, Wang G
And if you are eating less because the medication is doing its job suppressing appetite, you are also getting less fiber, less bulk, and less of the natural stimulation your colon needs to do its work
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Dynamic energy balance and obesity prevention