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Troglitazone Troglitazone was the first TZD approved for use in the United States and was licensed for use in T2DM in 1997, but withdrawn 3 years later because of the frequency of liver injury, including acute liver failure, associated with its use

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More education should be given to patients to try to prevent errors, especially considering injectable administration and weekly dosing may be new to many. To read the full study, click here.