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If you are escalating your dose during this period, expect a temporary return of heightened sensitivity with each increase
In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]
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Abstract Background l-carnitine is emerging as an item of interest for cardiovascular disease (CVD) prevention and treatment, but controversy exists