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Their multi-systemic effects include reducing de-novo lipogenesis, decreasing appetite via the brain, and offering cardiovascular protection

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Vitamin D, B12, niacin, selenium, and zinc support energy metabolism and overall cellular function

Because of their opposite functions on food intake and metabolic targets (Engelstoft & Schwartz, 2016), both hormones have gained traction as pharmacological targets for treatment of metabolic (i.e., obesity and type 2 diabetes (T2D)) and eating disorders (Atalayer et al., 2013

Randomized, placebo-controlled study of liraglutide 3 mg in 251 children ages 1217 with obesity that found a 4.6% reduction in BMI in the liraglutide group compared with placebo