tirzepatide in mash Study show beneficial for resolution of patients with MASH, fibrosis 🔴 #SYNERGY_NASH Trial (NEJM, 2024)

doi: 10.1016/S0140-6736(09)61375-1 11 AthaudaD.FoltynieT

Key Points Tirzepatide vs Semaglutide Tirzepatide targets both GLP-1 and GIP receptors, while Semaglutide primarily targets GLP-1 receptors

In Denmark, where semaglutide was developed, the drug costs $3,500 a year

It should be noted that Figure 2 is a simplified representation of the overall approach recommended by the ADA/EASD and includes only recommendations up to the point of dual antihyperglycemic therapy

The influences of drugs on the experimental constipation of mice treated with atropine and Papaverine

Modulate cytokine production, reducing pro-inflammatory signaling