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Oxidative stress can worsen the hypersensitive state of the central nervous system, which in turn can trigger pro-inflammatory factors that result in neurogenic inflammation

Diosgenin protects retinal pigment epithelial cells from inflammatory damage and oxidative stress induced by high glucose by activating AMPK/Nrf2/HO-1 pathway

Hassan SMA et al

Before Rybelsus was introduced in 2019, GLP-1 medications were only available as injections

This quick-reference table helps set patient expectations: nausea is common but often transient, and titration and supportive care usually shorten the course

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