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Clinical trials show approximately 24-29% weight loss with retatrutide versus ~15% with semaglutide and ~21% with tirzepatide
The cost asymmetry makes the quality gap worse, not better
however, no such studies have been undertaken in humans nor have anecdotal findings been reported in clinical trials on turmeric
But a whole world of cases exist in the gray area
In the landmark STEP-1 clinical trial, participants receiving semaglutide 2.4 mg once weekly lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% with placebo
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