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The primary one is competition from other GLP-1 drugs, especially from Eli Lillys Mounjaro (tirzepatide), which has shown greater efficacy in weight loss and diabetes control
Oral GLP-1 medications generally produce somewhat less weight loss than injectable versions in clinical data (16.6% vs
(Source: Chemist4U) People with a BMI over 45 reported an average life satisfaction score of 5.86/10 , which is about 20% lower than those with a BMI between 30 and 35
Why Weight Loss Medication Is Not Right for Everyone A treatment can be effective in clinical studies and still be difficult for an individual patient to tolerate or maintain
It is for patients with either: A body mass index (BMI) of 30 kg/m2 or greater A BMI of 27 kg/m2 or greater with at least one weight-related ailment such as type 2 diabetes, hypertension, sleep apnea, or others