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The qualitative or quantitative dysfunction of the regulatory T cells (Treg) leads to a series of autoimmune diseases with more established mechanisms [40]

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Sweeteners also function as excipients in various pharmaceuticals (Rowe et al, 2009), such as antihypertensives, and are co-ingested with long-term medications like antidepressants that are consumed by millions of people daily (World Population Review, 2022)

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3.2 Multiple hormonal disorders in GD may increase the risk of depression GD is not only an autoimmune disease but also an endocrine disease characterized by excessive secretion of thyroid hormones

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The same story is true for almost all over-the-counter painkillers, which is why theyre almost all considered non-steroidal anti-inflammatory drugs, or NSAIDs

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