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Based on the earlier discussed receptor expression, innervation and their crucial role in behavioral control two mesolimbic nuclei, the VTA and the NAc, became the first targets of studies exploring behavioral consequences of the mesolimbic GLP-1R activation
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Whether the superior effects of semaglutide and dulaglutide on stroke reduction compared to other GLP-1RAs arise from inherent differences in drug properties or disparities in trial design remains uncertain
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