Increasing usage means increasing rebates, and a PBM that doesnt fully pass rebates through will see this as a profit center
In models of high-fat diet-induced obesity, GLP-1R agonism has demonstrated the ability to enhance neurovascular coupling, improving the relationship between neuronal activity and blood flow in the brain
Rates of behavior and aging specified by mitochondrial function during development
Their results demonstrate that GLP-1, through an unknown mechanism, can preserve axonal and neurofilament structure despite the induction of progressive neurotoxicity, thus illustrating neuroprotective properties that can be leveraged against disorders in the central nervous system [60]
Long-term data on retatrutide is still pretty limited
Nevertheless, large database studies continue to show low incidence rates consistent with background population levels