Combined with the drop in TSH by 2 whole points, Id estimate that nigella sativa is roughly the equivalent to around 25 mcg of T4 thyroid hormone
Eaglesfield R, Fernandez-Vizarra E, Lacko E, Caldwell ST, Sloan NL, Siciarz D, et al
Transporter proteins such as ABCG2, OAT1, and OAT3 present on the epithelial cells of the renal proximal tubules serve as important outlets mediating urate excretion, while ABCC4, a known organic anion transporter protein, also plays a role in urate excretion, though its specific location remains unclear
4-8 weeks : This is the period during which weight changes will most likely be noticed, resulting in the loss of approximately 5-10% of body weight as dose increases and appetite stabilizes
PMID 15126349
How retatrutide compares to semaglutide and tirzepatide for appetite suppression Context matters