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Pooled and combined analyses Only five33 34 40 91 92 of the clinical trials above, all of which had shown a significantly positive effect of various GLP-1RAs on cognition, were comprised in a meta-analysis including 7732 individuals with T2DM, which however unexpectedly did not observe a benefit on cognitive scores (SMD 0.33
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Mutations in this receptor are associated with certain forms of type 2 diabetes
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