For visible results in a lighter tone/shade, 1-3 treatments are needed depending on skin type
The result is loose, hanging skin, most commonly around the abdomen, arms, thighs, and neck
First-timers should start low (1.25 mg subcutaneous or 1 mg intranasal) to gauge nausea tolerance before titrating up
While saline can be appropriate for isotonic delivery in some contexts, the preservative advantage makes it the only reasonable choice for any protocol that needs to draw from the same vial across more than a single day
for this reason, some clinicians recommend an intradermal test dose in individuals who may be at risk of thiamine allergy
Plastic containers may allow moisture to permeate