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The induction of GST genes or elevated GST activities has often been observed in plants treated with beneficial bacteria (Hassan et al., 2015
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Heffernan MA, Thorburn AW, Fam B, et al
--- Here are some potential actions covered in the article for payers and employers to take as a result of this shift: Update formulary tiers and step therapy policies (consider the impact on comorbidities) Support members transitioning off GLP-1s after reaching their goals Create differentiated access pathways based on patient risk profiles Monitor realworld outcomes beyond A1C (cardiovascular, renal, adherence) Model the downstream impact on generics and legacy therapies --- Commercial plans are accelerating GLP-1 uptake and favoring the simplicity of a single therapy
Bibcode:2015PLoSO..1019479L
So lets combine what we know so far into one major flowchart
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