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Based on this, in the subsequent I/R- and TMT-induced myocardial injury model, the drug not only enhanced GSH levels and GPX and GST activities to lower oxidative damage but also reduced TMT-induced pyroptosis and I/R-mediated apoptosis [205,206,207]
A polymorphism or variation in the sequence within an ER-response element located in the SELENOS promoter was found to result in reduced SELENOS promoter activity and gene expression (36)
Na2SeO3) was found to protect people from developing Keshan disease but could not reverse heart muscle damage once it had occurred (52)
We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)