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Mulcahy, Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element
However, In Colombia only some determinations have taken place in small groups (data without publishing), and there exist small work groups from certain universities like the Universidad del Rosario of Bogotas, who will soon give their results in relation to the prevalence of this alteration in the metabolism of hereditary type
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GLS1 is more broadly expressed in normal tissue, while GLS2 is mainly present in the liver, brain, pituitary gland, and pancreas [44]
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