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Human Reproduction Update , 25 , 673693

They trick the receptors into remaining turned on for prolonged periods of time

A pilot study subsequently conducted by Holst in collaboration with Mette Zander at Hvidovre Hospital between September 1999 and October 2000 indicated that continuous subcutaneous infusions of synthetic GLP-1 over 6 weeks into patients with quite severe type 2 diabetes dramatically improved their blood sugar control, lowered glycated haemoglobin levels and decreased their body weight

Their effects appear to be highly context-dependent

Nature Medicine, 19(5), 576

The company didnt announce prices for higher doses