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Genes involved in neuronal function displayed altered AS: sertraline treatment led to the inclusion of long isoforms of Ank2 , a gene associated with axonal stability, and of ATPalpha, a Na/K-ATPase subunit that maintains ionic gradients and neuronal excitability

Some people may need additional treatments, such as probiotics and/or antidiarrheal medication.

Comprehensive metabolome analyses reveal N -acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin