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retatrutide is investigational and not approved for any human use outside clinical trials

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Statements Author contributions EP: preparing the manuscript, manuscript revision, final approval of the version to be published

Coronary Artery Disease ( 1.2) Chronic Stable Angina Vasospastic Angina (Prinzmetal's or Variant Angina) Angiographically Documented Coronary Artery Disease in patients without heart failure or an ejection fraction 1% are fatigue, nausea, abdominal pain, and somnolence

Key Advantages: Targets hypothalamus-pituitary-gonadal axis directly, supports natural hormone signaling, short-term use efficacy

The subcutaneous route of administration allows for self-injection, typically in the abdomen, thigh, or upper arm