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136 Experimental models provide compelling evidence connecting inflammasome activation to APAP-induced liver injury
For example, 200-HPTChC53 (MW 200 kDa, 53% quaternisation) and 600-HPTChC65 (MW 600 kDa, 65% quaternisation) significantly increased paracellular transport in Caco-2 cells via TJ opening, with the latter also inhibiting P-glycoprotein-mediated efflux (Kowapradit et al., 2010
The most important results from the clinical studies involving danuglipron are shown in Table 1
136 , 476483.e5 (2023)
The neutral association observed with dulaglutide (HR: 0.91
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