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MOTS-c Mechanism and Dosing in the Stack Protocol MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded in mitochondrial DNA, not nuclear DNAmaking it one of the few bioactive compounds produced directly by the mitochondria
The problem is that translation from rodent models to human outcomes is notoriously unreliable, and we've been burned by promising animal data that didn't pan out in humans more times than anyone wants to count
includes warnings that parenteral thiamine may cause anaphylaxis and that the benzyl alcohol preservative is contraindicated in neonates due to risk of serious reactions)
Following these steps carefully ensures you get the full benefit of the peptides
"Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans"
& Smidt, M
