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That's the rule, and it doesn't change based on payer
In addition, the concentration of 5MTHF in the CSF is lower than normal in patients with idiopathic cerebral folate deficiency, and some patients also have reduced concentrations of CSF 5-hydroxyindoleacetic acid and biopterin
Both B12 shots and pills have pros and cons
Avoid repeated freeze-thaw cycles, which can degrade the peptides
Visible and measurable changes typically build over 4-8 weeks, then compound over 6-12 months
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