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Bischof K, Moitzi D, Stoop R, et al

For people with genetic variants that cause more of an impact on CYP1B1 upregulation combined with an inability to eliminate the estrogen metabolites fast enough (due to phase II genes, diet, and lifestyle) then cigarette smoking is going to significantly increase the bad estrogen metabolites

Samaneh Y, ShahidehJahanian S, Azadeh M, Anoshirvan K

Helps improve skin texture, tone, and elasticity

The research so far is promising, but more studies are needed to confirm findings and refine treatment protocols

Possible side effects include: Dryness Irritation Swelling Redness Hyperpigmentation and breakouts can become more visible briefly, and you can remove peeling skin gently