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In fact, many of the most compelling animal studies on BPC-157 use this very mechanism

Cytoskeleton 61 , 7482 (2005)

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For instance, PAGln significantly alleviates doxorubicin-induced cardiac toxicity via gut microbial metabolism regulation, reverses abnormal myocardial gene expression (e.g., Klb, Ece2, Casq1), and mitigates myocardial injury and apoptosis through mechanisms involving lipid metabolism, calcium signaling pathways, and store-operated Ca 2+ channel activity (Huang et al., 2025)

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