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#Healthcare #MedTech #HealthInnovation #DoctorsOfLinkedIn #HealthIT To view or add a comment, sign in Phase 3 TRANSCEND: Setmelanotide achieved a 16.5% reduction in BMI over 52 weeks by directly activating MC4R and bypassing impaired leptinPOMC signalingmarking a significant advance for patients with acquired hypothalamic obesity

While early findings are promising, more research is needed to understand the long-term effects when GLP-1s are used with other treatments (4,5)

Together, they explore the often-overlooked connections between hormone imbalances, nutrient deficiencies, thyroid dysfunction, autoimmune disease, and metabolic stressors like insulin resistance

Address sleep, nutrition, and smoking cessation

Prescription Assistance Programs: Some drug manufacturers and foundations offer prescription assistance programs to help patients access medications at a lower cost

Consult the complete retatrutide dosing guide for personalized recommendations