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While not as powerful as prescription GLP-1 drugs like Ozempic (which increase GLP-1 by 400%), supplements offer a safer, more affordable option for mild weight management expect 3-5 lbs of loss versus 15-20 lbs with prescriptions

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It has been suggested that patients with NAFLD have lower concentrations of biologically active incretin hormones compared to healthy individuals, which may be a consequence of an increased degradation by dipeptidyl peptidase 4 (DPP-4) (the enzyme, which under normal conditions inactivates the incretin hormones) (29) or a decreased production (30, 31)

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Receptor-interacting proteins (RIPK) 1 and RIPK3 are crucial components of this pathway

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