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Hormonal rebound Weight loss triggers increases in ghrelin (the hunger hormone) and decreases in leptin (the satiety hormone)

Physicians including gastroenterologists have been blunt that these products do not contain GLP-1 or a GLP-1 agonist and are unlikely to reproduce the drug's effect

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Throughout treatment, patients remain under clinical oversight, allowing for dosage adjustments and monitoring as needed

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1A), but with differences noted in EC 50 values for GEP44 (492.6 pM), GEP12 (17.3 nM) and Ex-4 (28.7 pM) at the GLP-1R (Fig