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Over a period of 21 days, the zebrafish received treatment with AST at concentrations of 10 and 20 mg/L, along with donepezil at 1 mg/L and the MMP-13 inhibitor CL-82198 at 10 M

108, 118 This is not surprising, given that the species-specific diet in mice is very different from humans who are omnivores and during much of their evolution consumed low-glycemic load diets

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doi: 10.1210/jcem.80.3.7883856 99 KiefferTJMcIntoshCHPedersonRA