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adults reported using weight loss medications in late 2025, more than double the 5.8% reported in February 2024

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Michigan BCBS implemented what amounted to a near-complete removal of weight loss indication coverage, with narrow exceptions for members who could demonstrate specific comorbidities beyond obesity alone

Malabsorption and genetic defects in the enzyme 5-methyltetrahydrofolate reductase (5-MTHFR) can result in an impaired ability to activate folic acid