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For combination protocols, published curves show the cagrilintide-plus-semaglutide arm pulling ahead of either single agent during this period (Frias et al., 2023)

Storage organization by form For unreconstituted (lyophilized) vials: Long-term supply (months out): freezer at -20C or below, in opaque container with desiccant Next vial to be reconstituted: can be moved to refrigerator a day or two before mixing Label each vial with the date received and the lot number if available For reconstituted vials: Always in the refrigerator at 2-8C Label with the reconstitution date and the planned discard date (30 days from mixing) Store in an opaque container or wrap in foil Keep away from the door and away from any food items with strong odors This organizational approach is the same system that works for managing tirzepatide vial lifespan and semaglutide vial shelf life

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The 1-RM was recorded as the maximum weight that the participant could lift for 1 repetition