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In preclinical models, these mechanisms translate into broad potential applications, including wound healing, muscle and tendon repair, gastrointestinal ulcer protection, and recovery from NSAID-induced damage

Zhao L, Han XM, Wang W, Yang HL (2014) Molecular and catalytic properties of glutathione peroxidase family proteins from Pinus tabulaeformis

Glutathione peroxidases (GPx), selenium-containing enzymes, require two molecules of reduced glutathione to break down hydroperoxides

It may also be given under the tongue, as a pill, or as a nasal spray

The pace of free radical generation, however, can often surpass the cellular production of glutathione (GSH), leading to a cascade of oxidative stress, chronic inflammation and tissue damage

The biochemistry and physiology of s-nitrosothiols