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Animal Model Evidence The systemic evidence base is entirely preclinical: Pulmonary fibrosis (mouse model): Intraperitoneal GHK-Cu at 0.2-20 micrograms/g/day protected against bleomycin-induced lung fibrosis by inhibiting TGF-beta1/Smad signaling and reducing oxidative stress (PMID 31809714)
Predrag Sikiric
10.1158/0008-5472.Can-20-1488 159 WangY.ZhaoG.CondelloS.HuangH.CardenasH.TannerE
Both routes end in growth hormone release, but they start from different doors
For the mechanistic, stem-cell-level version of this discussion, the companion piece on how GHK-Cu affects hair-follicle stem cells and hair growth examines the cellular pathways in detail
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