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From their beginnings as a treatment for type 2 diabetes, GLP-1 receptor agonists such as the semaglutide drugs Ozempic and Wegovy and the tirzepatide drugs Mounjaro and Zepbound have seen an explosion in use, most popularly for weight loss
Proportions are based on the number of participants at risk
The slides were mounted with a solution containing DAPI (Molecular Probes) and imaged using a Leica TCS SP8 laser scanning confocal microscope (Leica Microsystems CMS GmbH, Wetzlar, Germany)
Both genetic and environmental models demonstrate reduced taste receptor expression, especially in the hypothalamus and brainstem, but no significant changes in cortical or hippocampal expression (123)
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