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however, its availability and use are restricted to research purposes unless prescribed by a licensed medical provider

The TCF7L2 Gene: Your GLP-1 Regulator The TCF7L2 gene is a GLP-1 regulator and its important because it: Directly regulates the production and secretion of GLP-1 Influences how well GLP-1 can stimulate insulin release Its strongly linked to type 2 diabetes risk (the strongest genetic risk factor identified!) When you have certain variants of TCF7L2, your body produces less GLP-1 and responds more weakly to the GLP-1 you do produce

Patient Scenarios: Real World Decision Making Sarah, 52, with type 2 diabetes and heart disease : Sarahs provider chose Ozempic over Trulicity specifically because cardiovascular outcome trials demonstrated significant reductions in major adverse cardiac events with semaglutide

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It is identified in the clinical-research literature under the development designation LY3437943 and is currently in Phase 3 evaluation under the TRIUMPH trial program

These descriptions do not establish that GLP-1 medications cause these conditions