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Effects of vitamin B12 deficiency can result in a range of negative health effects

A DSM study from the human nutrition and health department (59) describes hydroxytyrosol as the most powerful anti-inflammatory compound among polyphenols of olive oil, showing effective inhibition in the production of NO and PGE2, decreasing secretion of cytokines (IL-1, IL-1, IL-6, IL-12, TNF-) and chemokines (CXCL10/IP-10, CCL2/MPC-1) and reducing gene expression of iNOS, IL-1, CXCL10/IP-10, MIP-1, matrix metaloproteinase-9, and prostaglandin E2 synthase (PGES)

PubMed laboratory research record [PMID: 23910417] PubMed record related to this compound for laboratory literature review

In: StatPearls [Internet]

Lowered Quality of Life: Chronic pain can lead to frustration and decreased enjoyment of lifes activities

Flanagan, J