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In prostate cancer cells, phenethyl isothiocyanate, a phytochemical found in large amounts in cruciferous vegetables, was reported to restore expression of silenced GSTP1 by a mechanism involving promoter demethylation and increased histone acetylation
As such, healthcare providers should exercise caution and rely on the most current research when considering glutathione suppositories for off-label applications
Both have been on the FDAs drug shortage list since 2022
Regular follow-up helps determine whether treatment goals are being achieved safely
Accessed April 9, 2024
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